Join the Munschauer Lab at the Centre for Integrative Infectious Disease Research (CIID) and explore how RNA interactions can be harnessed to improve therapeutic mRNA. As part of the newly established DFG Collaborative Research Centre CRC/TRR 440 smART, you will investigate RNA-protein interactions and develop innovative strategies to enhance mRNA performance. Our international and interdisciplinary team combines RNA biochemistry, cell biology, mass spectrometry, genomics, single-cell transcriptomics and bioinformatics to understand RNA regulation at high spatial and temporal resolution. You will benefit from state-of-the-art research approaches, close collaboration with wet-lab scientists and bioinformaticians, structured doctoral training and excellent opportunities to develop your scientific profile.
Dissect and characterize cellular RNA-protein interactions with high spatial and temporal resolution
Recombinantly produce and purify RNA-binding proteins and characterize their binding preferences using biochemical and biophysical methods
Synthesize mRNA in vitro and formulate it into lipid nanoparticle delivery systems
Characterize lipid nanoparticles through appropriate quality-control experiments
Use cell-based assays to investigate RNA delivery, intracellular transport, stability, translation, decay and payload expression
Collaborate closely with scientists across CRC/TRR 440 smART and contribute to interdisciplinary research activities
Work at the interface of experimental RNA biology, biochemistry and bioinformatics within an international research team
You hold a Master’s degree or an equivalent qualification in cell biology, biochemistry or a related field in the natural or life sciences
Practical experience in RNA biochemistry, cell biology and biophysical methods provides a strong foundation for your doctoral research
Previous experience with lipid nanoparticle formulation is an advantage, but not a prerequisite
Professional proficiency in written and spoken English enables you to communicate and collaborate effectively in an international research environment
Scientific curiosity, accuracy and the ability to conduct research independently, combined with enthusiasm for interdisciplinary teamwork, complete your profile
Remuneration according to TV-L E 13 and an attractive employer-funded pension scheme through VBL
30 days of annual leave
Sustainable mobility with the Deutschlandticket
A family-friendly working environment with childcare cooperation, subsidies for holiday childcare and support for employees caring for relatives
A wide range of health, prevention and sports programmes
A doctoral research project at the interface of RNA biology, RNA biochemistry and therapeutic mRNA development
Goal-oriented individual training and development, including the doctoral study programme of the Department of Infectious Diseases and the integrated graduate school of CRC/TRR 440 smART
Access to modern technologies and technical infrastructure for RNA biology research
The opportunity to complete a doctorate and active support in publishing your research in scientific journals
Regular team meetings and close collaboration within an international and interdisciplinary research environment
Scientific networking within CRC/TRR 440 smART, including collaborative activities and annual retreats
Participation in a three-day summer school within the smART graduate training programme
Source: Bundesagentur fur Arbeit — German Federal Employment Agency · Retrieved 2026-11-10 · Not affiliated with or endorsed by the German Federal Employment Agency
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